Comparison Between Colloid and Crystalloid Infusions in the Prevention of Postspinal Hypotension in Cesarean Deliveries

Majid Razavi, Arash Peivandi Yazdi, Nahid Zirak, Mohammad Masoum Zadeh, Mehryar Taghavi Gilani


Background and Aim: Hypotension is an important serious side effect of spinal anesthesia.

The aim of the study was to compare the efficacy of administering colloid and crystalloid solution with spinal anesthesia during cesarean surgeries to prevent hypotension.

Materials and Methods: The study included 100 spinal anesthesia patients who underwent elective cesarean surgery in 4 groups. In groups 1 and 2, 7 cc/kg of colloid solution was injected 20 min before and during spinal anesthesia, respectively. In groups 3 and 4, 15 cc/kg of Ringer solution was injected 20 min before and during spinal anesthesia, respectively. The BP, heart rate changes, vasopressor dose, nausea, vomiting, chest discomfort, and Apgar score were evaluated.

Results: The BP decreased significantly when the patients changed position from supine to seating position (P = .001) and in the third minute after injecting the local anesthetic (P = .031) in all groups. Group 4 (23.5%) patients exhibited significant hypotension, whereas group 2 (15.9%) patients showed less hypotension. However, there was no statistically significant difference between the 4 groups (P = .31). There were no statistical differences between the 4 groups in the Apgar of the fifth minute, vomiting, vertigo, and chest discomfort.

Conclusions: Owing to high cost and probable side effects, colloid solutions are not recommended; and emergency cesareans need not be postponed to perform hydration before spinal anesthesia.

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